Hi, I found two omega nodes who reduce the damage of your hero, when you pick them, when it is clear that they are nodes for damage boosting.
First:
Human Augmentation
Cybernetic Claws
maxed, it reduce base damage by -10%, and increase crit damage by +30%
So it increase your crit damage from 200% to 230%, on the cost of 10% base damage.
Small caculation
10000 base damage, 200% crit = 30000 final damage
10000 base damage * 0,9 = 9000 base damage, 230% crit = 29300 final damage.
Loose, 700 dmg per crit, 1000 dmg per normal hit.
It becomes even worse, with better crit rating and higher base damage nunbers.
Second:
Amadeus Cho:
-25% brutal damage strike rating, grants 6% crit rating.
by 50% crit, 50% base, 200% crit damage, 400% brutal damage
100 hits a 1 damage
50 hits normal 1 damage
50 crits(25 normal, 25 brutal)
25 hits crit 3 damage
25 hits brutal 5 damage
= 125+75+50=250 final damage
now with cho:
100 hits a 1damage
44hits a 1 damage
56crits(42crits, 14brutal)
42 hits crit a 3damage
14 hits brutal a 5damage
= 70+126+44=240damage
loose 10 damage.
Please, write more nodes you found. Where you think they are damage increase, but in reality they decrease the damage if you skill them.